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Vinorelbine tartrate CAS 125317-39-7
Chemical PropertiesAppearance: white to off-white crystalline powder Molecular Weight: 1079.10594 Density: 1.36g/cm3 Melting Point: 181-183°C Storage Temperature: 2-8°C Refractive index: 1.675 Solubility: 10 mg/mL in ** Biological Activity: Selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. Inhibits proliferation of multiple human tumor cell lines (IC 50 = 1.25 nM in HeLa cells) and blocks metaphase/anaphase transition by suppression of microtubule dynamics (IC 50 = 3.8 nM). Reduces spindle length by 29% and inhibits microtubule polymerization at micromolar concentrations. Usage: An antineoplastic Safety Data of 125317-39-7
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