Dexrazoxane右雷左生

更新时间：2018-03-09

CAS号：24584-09-6

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Dexrazoxane CAS 24584-09-6

Chemical Properties Molecular Weight: 268.27 Density: 1.333 g/cm3 Boiling Point: 531.5 °C at 760 mmHg Melting Point: 194-196℃ Flash Point: 531.5 °C at 760 mmHg Refractive index: 1.539 Solubility: Slightly soluble in methanol and ethanol. Insoluble in non polar organic solvents. Solubility (mg/mL): 35-43 0.1 N HCl, 25-34 0.1 N NaOH, 6.7-10 0.1 M citrate buffer (pH 4), 8.7-13 0.1 M borate buffer (pH 9) In **, 10-12 mg/mL at 25 deg C Biological Activity: Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway. Safety Data of 24584-09-6

Chemical Properties

Molecular Weight:

268.27

Density:

1.333 g/cm3

Boiling Point:

531.5 °C at 760 mmHg

Melting Point:

194-196℃

Flash Point:

531.5 °C at 760 mmHg

Refractive index:

1.539

Solubility:

Slightly soluble in methanol and ethanol. Insoluble in non polar organic solvents.
Solubility (mg/mL): 35-43 0.1 N HCl, 25-34 0.1 N NaOH, 6.7-10 0.1 M citrate buffer (pH 4), 8.7-13 0.1 M borate buffer (pH 9)
In **, 10-12 mg/mL at 25 deg C

Biological Activity:

Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway.

Safety Data of 24584-09-6

HOT PRODUCT

以下信息来自CAS号查询大全，前往了解更多：24584-09-6

Dexrazoxane右雷左生CAS号：24584-09-6

Dexrazoxane右雷左生分子式： C11H16N4O4

24584-09-6

Dexrazoxane右雷左生英文名称： Dexrazoxane

Dexrazoxane右雷左生英文同义词： (+)-4,4'-(1-Methyl-1,2-ethanediyl)bis-2,6-piperazinedione; (+)-4,4'-Propylenedi-2,6-piperazinedione; (S)-4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-2,6-PIPERAZINEDIONE; 2,6-piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-; 4,4'-(2S)-Propan-1,2-diyldipiperazin-2,6-dion; 4,4'-(2S)-Propane-1,2-diyldipiperazine-2,6-dione; 4,4'-(2S)-propane-1,2-diyldipipérazine-2,6-dione; 4,4'-[(2S)-1,2-Propanediyl]di(2,6-piperazinedione); Eucardion

Dexrazoxane右雷左生分子量： 268.2691

Dexrazoxane右雷左生熔点： 194-196℃

Dexrazoxane右雷左生沸点： 531.5°C at 760 mmHg

Dexrazoxane右雷左生密度： 2.22E-11mmHg at 25°C

Dexrazoxane右雷左生闪点： 275.3°C

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