Anastrozole CAS NO.120511-73-1 active pharmaceutical ingredient
Chemical Properties
Appearance:
crystalline solid
Molecular Weight:
293.37
Density:
1.08 g/cm3
Boiling Point:
469.7 ℃ at 760 mmHg
Melting Point:
81-82℃
Flash Point:
469.7 oC at 760 mmHg
Storage Temperature:
Store in original container in a cool dark place.
Refractive index:
1.791
Solubility:
Insoluble
Biological Activity:
Potent and highly selective aromatase (CYP19) inhibitor (IC 50 = 5nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo. Orally active.
Usage:
An aromatase inhibitor. Used as an antineoplastic.
