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Chemical Properties
Appearance:
Orange-yellow to deep yellow solid or powder
Molecular Weight:
300.05
Density:
3.7
Melting Point:
270℃
Storage Temperature:
Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep containers tightly closed.
Solubility:
<0.1 g/100 mL at 19 oC in **
Biological Activity:
Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF- α -induced apoptosis.
Stability:
Stable. Incompatible with oxidizing agents, aluminium, antioxidants.
Usage:
Used as an antineoplastic
Safety Data of 15663-27-1
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